56 Analysis of Xa Levels and PTTs During the First 48 Hours of Anticoagulation with Unfractionated Heparin Infusion

Introduction: For acute venous thromboembolism (VTE), the CHEST guidelines recommend a PTT goal of 1.5 to 2.5 times the control or anti-factor Xa level of 0.3 - 0.7 units/mL. In 2021, our institution added nurse-driven Xa nomograms to titrate heparin infusion. The objective of this study is to determine the proportion of patients on heparin infusion for VTE that achieved therapeutic Xa level or PTT within the first 48 hours of initiating heparin infusion.