64 Variation in Anticoagulant Hemorrhage Management Guidelines for Factor-Xa Inhibitors: A Survey and Analysis of U.S. Academic Institutions
Introduction: Before Andexanet alfa (AA) was approved by the United States (US) Food and Drug Administration in 2018, inactivated three- and four-factor prothrombin complex concentrates (3F-PCC and 4F-PCC) were the primary off-label options for managing factor-Xa inhibitor-associated hemorrhage. We aimed to compare institutional guidelines for factor-Xa inhibitor hemorrhage management.
Authors
- Radhika Gangaraju (ORCID: https://orcid.org/0000-0002-5542-4754)
- Diana M. Byrnes (ORCID: https://orcid.org/0000-0003-0781-7577)
- Ming Y. Lim (ORCID: https://orcid.org/0000-0001-5208-3387)
- Jacob C. Cogan (ORCID: https://orcid.org/0000-0003-4036-7838)
- Karlyn A. Martin (ORCID: https://orcid.org/0000-0002-9385-8705)
- Kimberley Youkhana (ORCID: https://orcid.org/0000-0002-3188-4465)
- Andrew M. Peseski (ORCID: https://orcid.org/0000-0002-5114-611X)
- Manila Gaddh (ORCID: https://orcid.org/0000-0002-0817-9848)
- Rachel Rosovsky (ORCID: https://orcid.org/0000-0002-2392-7365)
- Lisa Baumann Kreuziger (ORCID: https://orcid.org/0000-0002-1171-0548)
- John A. Sibley
- Ishan Tatake (ORCID: https://orcid.org/0009-0004-1558-021X)
- Rishabh Singh (ORCID: https://orcid.org/0000-0002-8950-4277)
Institutions
- University of Vermont (US)
- University of Minnesota (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- University of Miami (US)
- Emory University (US)
- Medical University of South Carolina (US)
- Illinois College (US)
- Medical College of Wisconsin (US)
- University of Utah (US)
- University of Alabama at Birmingham (US)
- University of Illinois Chicago (US)
- Massachusetts General Hospital (US)
- Versiti Blood Center of Wisconsin (US)
- Duke Medical Center (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.102813
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00