142 Evaluation of Direct Oral Anticoagulant Eligibility and Prescribing for Primary Venous Thromboembolism Prevention in High-Risk Ambulatory Patients with Cancer

Introduction: Venous thromboembolism (VTE) significantly impacts morbidity and mortality in patients with active cancer. Venous thromboembolism in patients with cancer can disrupt or delay treatment, potentially worsening outcomes. Long-term effects of VTE, such as post-thrombotic syndrome and chronic thromboembolic pulmonary hypertension, can diminish quality of life and impose substantial financial burdens. Historically, thromboprophylaxis was limited to parenteral anticoagulants which presents as a challenge for patient self-administration in the ambulatory setting.

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Publication Details

Journal
Research and Practice in Thrombosis and Haemostasis
Published
2025-05-01
DOI
https://doi.org/10.1016/j.rpth.2025.102818
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

142 Evaluation of Direct Oral Anticoagulant Eligibility and Prescribing for Primary Venous Thromboembolism Prevention in High-Risk Ambulatory Patients with Cancer

Kathryn Dane, Lei Zheng, Daniel A. Laheru, Stefanie Houseknecht et al.
Research and Practice in Thrombosis and Haemostasis
Venous Thromboembolism Diagnosis and Management
article

142 Evaluation of Direct Oral Anticoagulant Eligibility and Prescribing for Primary Venous Thromboembolism Prevention in High-Risk Ambulatory Patients with Cancer

Kathryn Dane, Lei Zheng, Daniel A. Laheru, Stefanie Houseknecht, Michelle Wasan, Michael B. Streiff, Kelli Rourke, Charita Marthone
article en

Abstract

Introduction: Venous thromboembolism (VTE) significantly impacts morbidity and mortality in patients with active cancer. Venous thromboembolism in patients with cancer can disrupt or delay treatment, potentially worsening outcomes. Long-term effects of VTE, such as post-thrombotic syndrome and chronic thromboembolic pulmonary hypertension, can diminish quality of life and impose substantial financial burdens. Historically, thromboprophylaxis was limited to parenteral anticoagulants which presents as a challenge for patient self-administration in the ambulatory setting.

Research and Practice in Thrombosis and HaemostasisVol. 9
Johns Hopkins University (US), Johns Hopkins Medicine (US), Johns Hopkins Bayview Medical Center (US), Sibley Memorial Hospital (US), Johns Hopkins Hospital (US)
Good health and well-being
Openalex Percentile: Top 74%
Venous Thromboembolism Diagnosis and Management
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142 Evaluation of Direct Oral Anticoagulant Eligibility and Prescribing for Primary Venous Thromboembolism Prevention in High-Risk Ambulatory Patients with Cancer — Kathryn Dane, Lei Zheng, et al. · Research and Practice in Thrombosis and Haemostasis (2025) | TGRS Research Map | TGRS