91 Making It Count: Evaluating an Intervention to Increase Usability of Factor Xa Inhibitor Anti-Xa Levels

Introduction: Apixaban and rivaroxaban are commonly ordered oral anticoagulants, which inhibit clotting factor X (factor Xa inhibitors, FXai). There are no Federal Drug Administration (FDA) approved laboratory assessments available to measure the anticoagulant effects of FXais. Furthermore, obtaining these levels is not recommended due to lack of information regarding their utility, and significant variability in levels depending on the timing of lab in relation to patient's last dose. Sanford USD Medical Center has lab capabilities to analyze and report FXai levels.