Pharmacological assessment of <i>Coffea arabica</i> compounds as potential therapeutics for cervical cancer
The data supporting the findings of this study, including bulk RNA-seq gene expression data, survival, and phenotype data, are available through the TCGA database. These data can be accessed via the Xenabrowser platform (https://xenabrowser.net) using the reference identifier [TCGA Cervical Cancer (CESC)]. Corresponding healthy cervical tissue RNA-seq data, are available through the Genotype-Tissue Expression (GTEx) project (https://www.gtexportal.org/home/). The codes used for differential gene expression (DGE) analysis, pathway enrichment, and survival analysis, as well as scripts for generating volcano plots (DGE analysis), Kaplan-Meier survival plots, and boxplots (gene expression), and machine learning implementations are available on GitHub (https://github.com/Ponaskillzyy/Coffea_arabica_Potential_in_Cervical_Cancer).
Authors
- Victor Omoboyede (ORCID: https://orcid.org/0000-0003-1973-0882)
- John Oluwagbenga Balogun
- Haruna Isiyaku Umar (ORCID: https://orcid.org/0000-0001-9427-9804)
- Prosper Obed Chukwuemeka (ORCID: https://orcid.org/0000-0001-8381-2802)
- Christopher Busayo Olowosoke (ORCID: https://orcid.org/0000-0002-4315-3184)
- Daniel Okpaise (ORCID: https://orcid.org/0009-0000-4982-4332)
- Nwachukwu Christiana Okonkwo (ORCID: https://orcid.org/0009-0006-2251-6341)
- Onyekachi Victor Onyedikachi (ORCID: https://orcid.org/0000-0003-4091-3771)
- Rita Ononiwu (ORCID: https://orcid.org/0009-0007-4046-0115)
- Sarah Olanrewaju Oladejo (ORCID: https://orcid.org/0000-0003-3320-7422)
Institutions
- Lagos State University (NG)
- Bells University of Technology (NG)
- Federal University of Technology (NG)
- University of Ibadan (NG)
- Nnamdi Azikiwe University (NG)
- Ondo State Primary Health Care Development Board (NG)
- Lead City University (NG)
- Michael Okpara University of Agriculture (NG)
Publication Details
- Journal
- Bioinformatics Advances
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1093/bioadv/vbaf132
- Citations
- 3
- Primary Topic
- Antioxidant Activity and Oxidative Stress
- Type
- article
- Field-Weighted Citation Impact
- 0.67