Vortioxetine for the Treatment of Depression in Patients with Parkinson's Disease: A 16-week Pilot, Prospective, Open-label Safety Study

Vortioxetine is a safe and well-tolerated therapeutic approach for depression in Parkinson's disease. As a secondary objective, an improvement in depressive symptoms was observed. However, the study's open-label design and small sample size limit the generalizability of the findings.

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Publication Details

Journal
Current Neuropharmacology
Published
2025-06-02
DOI
https://doi.org/10.2174/011570159x361647250416072053
Citations
2
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
2.78
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article

Vortioxetine for the Treatment of Depression in Patients with Parkinson's Disease: A 16-week Pilot, Prospective, Open-label Safety Study

Daniele Bravi, Cecilia Coletti, Laura Vacca, Fabrizio Stocchi et al.
2 citations
Current Neuropharmacology
Parkinson's Disease Mechanisms and Treatments
2.78
article

Vortioxetine for the Treatment of Depression in Patients with Parkinson's Disease: A 16-week Pilot, Prospective, Open-label Safety Study

Daniele Bravi, Cecilia Coletti, Laura Vacca, Fabrizio Stocchi, Fabiana Giada Radicati
article en
2 citations

Abstract

Vortioxetine is a safe and well-tolerated therapeutic approach for depression in Parkinson's disease. As a secondary objective, an improvement in depressive symptoms was observed. However, the study's open-label design and small sample size limit the generalizability of the findings.

Current NeuropharmacologyVol. 23(1)
Vita-Salute San Raffaele University (IT), San Raffaele University of Rome (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Good health and well-being
Openalex Percentile: Top 10%
Parkinson's Disease Mechanisms and Treatments
2.78
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Vortioxetine for the Treatment of Depression in Patients with Parkinson's Disease: A 16-week Pilot, Prospective, Open-label Safety Study — Daniele Bravi, Cecilia Coletti, et al. · Current Neuropharmacology (2025) | TGRS Research Map | TGRS