Differentiating Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Responses Between Infection and Vaccination: Challenges for Epidemiological Research
Some common coronavirus disease 2019 (COVID-19) vaccines elicit antibody responses that most serological tests are unable to differentiate from an infection response. This presents a challenge for COVID-19 epidemiology and serosurveys. In this perspective, we examine the potential scale of this problem.
Authors
- Karen E Walker-Bone (ORCID: https://orcid.org/0000-0002-5992-1459)
- Paul V. Licciardi (ORCID: https://orcid.org/0000-0001-6086-6285)
- Matthew Carroll (ORCID: https://orcid.org/0000-0002-6396-8364)
- Sunav N Nayagam
- Michael John Abramson (ORCID: https://orcid.org/0000-0002-9954-0538)
- Tyler Lane (ORCID: https://orcid.org/0000-0001-6089-1827)
- Zheng Quan Toh (ORCID: https://orcid.org/0000-0002-0282-5837)
- William Coote
Institutions
- The Royal Melbourne Hospital (AU)
- The University of Melbourne (AU)
- Parks Victoria (AU)
- Monash Health (AU)
- Murdoch Children's Research Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-05-31
- DOI
- https://doi.org/10.1093/infdis/jiaf295
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00