Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis

While pediatric CRCs overall more often demonstrate advanced stages, unfavorable histology, and a poorer prognosis than adult CRC, MSI is more common in pediatric CRC and is associated with superior survival.

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Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-06-02
DOI
https://doi.org/10.1002/pbc.31830
Citations
1
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
1.47

Funders

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article

Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis

Leo Kager, Antje Redlich, Michaela Kuhlen, Abbas Agaimy et al.
1 citations
Pediatric Blood & Cancer
Genetic factors in colorectal cancer
1.47
article

Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis

Leo Kager, Antje Redlich, Michaela Kuhlen, Abbas Agaimy, Ines B. Brecht, Jörg Fuchs, Hannah Wild, Andreas Block, Udo Kontny, Alexandra Liebmann, Andreas Schmidt, Michael Abele, Linda Maschke, Dominik T. Schneider, Lucas Maennel
article en
1 citations

Abstract

While pediatric CRCs overall more often demonstrate advanced stages, unfavorable histology, and a poorer prognosis than adult CRC, MSI is more common in pediatric CRC and is associated with superior survival.

Pediatric Blood & CancerVol. 72(8)
Universität Hamburg (DE), University of Augsburg (DE), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Universitätsklinikum Erlangen (DE), University Medical Center Hamburg-Eppendorf (DE), Universitätsklinikum Aachen (DE), St Anna Children's Hospital (AT), University Children's Hospital Tübingen (DE), Klinikum Dortmund (DE), St. Anna Children's Cancer Research Institute, University of Tübingen (DE), Otto-von-Guericke-Universität Magdeburg (DE)
Deutsche Kinderkrebsstiftung
No poverty
Openalex Percentile: Top 19%
Genetic factors in colorectal cancer
1.47
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