Multi-microRNA Diagnostic Panel for Heart Failure with Preserved Ejection Fraction in Preclinical and Clinical Settings
A panel of four circulating miRNAs was differently expressed in female HFpEF rats and significantly discriminated HFpEF patients from healthy individuals and HFrEF patients. This cross-species and bench-to-bedside approach demonstrates the potential of miRNA-based panels for HFpEF diagnosis.
Authors
- Emeline M. Van Craenenbroeck (ORCID: https://orcid.org/0000-0001-7686-2668)
- Volker Adams (ORCID: https://orcid.org/0000-0002-7955-7324)
- Ulrik Wisløff (ORCID: https://orcid.org/0000-0002-7211-3587)
- Reza Parvan (ORCID: https://orcid.org/0000-0002-1973-2813)
- Alessandro Cataliotti (ORCID: https://orcid.org/0000-0001-5476-8523)
- Andreas B. Gevaert (ORCID: https://orcid.org/0000-0002-1338-4133)
- Gustavo José Justo da Silva (ORCID: https://orcid.org/0000-0002-1651-7966)
- Natale Rolim (ORCID: https://orcid.org/0000-0003-3469-9932)
Institutions
- Oslo University Hospital (NO)
- University of Antwerp (BE)
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- University of Oslo (NO)
- Norwegian University of Science and Technology (NO)
- Antwerp University Hospital (BE)
- Institutt for Eksperimentell Medisinsk Forskning (NO)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1002/ehf2.15324
- Citations
- 5
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 6.94
Funders
- Stiftelsen Kristian Gerhard Jebsen
- European Commission
- European Society of Cardiology
- Nasjonalforeningen for Folkehelsen