Posterior Mediastinal Neuroblastoma in Children: An Unusual Location

Neuroblastoma is the most common neurogenic tumor in children, primarily affecting those under 5 years old. It often arises from immature neural crest cells, commonly in the adrenal medulla, but can also occur in the posterior mediastinum. A 4-year-old child presented with cervical lymphadenopathy and a right apical opacity on chest X-ray. CT revealed a lesion in the right posterior-superior mediastinum, confirmed as neuroblastoma upon pathological examination. The patient received neoadjuvant chemotherapy but passed away before surgery. Neuroblastoma is highly heterogeneous, with varied symptoms based on age and tumor location. Imaging is crucial for diagnosis and assessing tumor extent. Posterior mediastinal neuroblastoma is rare in children, presenting diagnostic challenges. Imaging aids detection, while histological analysis confirms the diagnosis

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Publication Details

Journal
Scholars Journal of Medical Case Reports
Published
2025-05-23
DOI
https://doi.org/10.36347/sjmcr.2025.v13i05.092
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Posterior Mediastinal Neuroblastoma in Children: An Unusual Location

B. Zouita, D. Basraoui, J. Ait Si Abdessadeq, S. Ouassil et al.
Scholars Journal of Medical Case Reports
Neuroblastoma Research and Treatments
article

Posterior Mediastinal Neuroblastoma in Children: An Unusual Location

B. Zouita, D. Basraoui, J. Ait Si Abdessadeq, S. Ouassil, H. Jalal, H. Chenter, H-C. Ahmanna
article en

Abstract

Neuroblastoma is the most common neurogenic tumor in children, primarily affecting those under 5 years old. It often arises from immature neural crest cells, commonly in the adrenal medulla, but can also occur in the posterior mediastinum. A 4-year-old child presented with cervical lymphadenopathy and a right apical opacity on chest X-ray. CT revealed a lesion in the right posterior-superior mediastinum, confirmed as neuroblastoma upon pathological examination. The patient received neoadjuvant chemotherapy but passed away before surgery. Neuroblastoma is highly heterogeneous, with varied symptoms based on age and tumor location. Imaging is crucial for diagnosis and assessing tumor extent. Posterior mediastinal neuroblastoma is rare in children, presenting diagnostic challenges. Imaging aids detection, while histological analysis confirms the diagnosis

Scholars Journal of Medical Case ReportsVol. 13(05)
Openalex Percentile: Top 80%
Neuroblastoma Research and Treatments
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