Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis

BAL lymphocytosis and eosinophilia are associated with ICIP, but their ability to discriminate ICIP from other conditions is modest. BAL immune cell percentages may have prognostic value for 1-year survival, but this likely reflects the morbidity of other pulmonary diseases that require BAL for evaluation.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-06-02
DOI
https://doi.org/10.3389/fmed.2025.1582714
Citations
3
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
3.14
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Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis

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article

Bronchoalveolar lavage cell percentages as diagnostic markers of immune checkpoint inhibitor pneumonitis

Karthik Suresh, Aung Naing, Jia Wu, David E. Ost, Roberto Adachi, Vickie R. Shannon, Arumugam Suresh, Roberto F. Casal, Qiong Gan, Lara Bashoura, Mehmet Altan, Diwakar D. Balachandran, Mahnoor Mir, Saadia A. Faiz, Julie Qiaojin Lin, Burton F. Dickey, George A. Eapen, Ajay Sheshadri, Jianjun Gao, Horiana B. Grosu, Scott E. Evans, Bruce F. Sabath, Carlos A. Jimenez, Pedro Antonio Amezcua Gomez, Rodrigo Del Rio Arroyo, Felipe Soto, Amber Su, John Stewart
article en
3 citations

Abstract

BAL lymphocytosis and eosinophilia are associated with ICIP, but their ability to discriminate ICIP from other conditions is modest. BAL immune cell percentages may have prognostic value for 1-year survival, but this likely reflects the morbidity of other pulmonary diseases that require BAL for evaluation.

Frontiers in MedicineVol. 12
The University of Texas MD Anderson Cancer Center (US), Johns Hopkins University (US), The University of Texas Health Science Center (US), Spanish Oncology Genitourinary Group (ES), Texas A&M University (US), Tecnológico de Monterrey (MX)
Openalex Percentile: Top 8%
Cancer Immunotherapy and Biomarkers
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