Formulation and evaluation of orodispersible tablet of cimetidine

The main goal of this study is to create and compare the orodispersible capsules of H2 blockers using a direct compression method.All of the formulations had been arranged using three super disintegrants.All the formulations have been tested for various parameters like hardness, weight, friability, wetting time, and many others to ensure their quality.The formulations were evaluated in a lab environment and were selected primarily on the basis of their hardness, wetting time, and disintegration time.The final outcomes revealed that the disintegration time decreased as a result of the utilization of exceptional disintegrants, and the drugs also exhibited the desired hardness.This is likely because of the high wicking and capillary action of crosspovidone, as well as its greater gelling tendency compared to sodium starch glycolate and crosscarmellose sodium.Among all the six formulations, the exceptional system was selected as the one to change An extremely efficient disintegrant was used in the creation of a quick-acting medication delivery system for cimetidine.