EVALUATING THE IMPACT OF FRESH FROZEN PLASMA (FFP) VERSUS NON-FFP PRIMING ON POSTOPERATIVE BLEEDING IN CHILDREN <10 YEARS UNDERGOING CARDIAC SURGERY: A PROSPECTIVE SINGLE-CENTER EXPERIENCE BELAGAVI, KARNATAKA.

BackgroundLimited research in India has explored the use of fresh frozen plasma (FFP) as a priming solution in pediatric open-heart surgery.The optimal cardiopulmonary bypass (CPB) circuit priming solution remains debated ObjectiveThis study aimed to evaluate the effects of FFP versus non-FFP priming solutions on metabolic variables, coagulation profiles, postoperative bleeding, and colloidal oncotic pressure in pediatric Cardiopulmonary bypass patients at the tertiary care hospital of Belagavi, Karnataka MethodsA prospective observational study was conducted at a tertiary care hospital in Karnataka.Sixty-four pediatric patients under 10 years undergoing elective open heart surgery requiring CPB were randomly assigned to receive either FFP (FFP group) or non-FFP (Non-FFP group) as a priming solution.Preoperative clinical, biochemical, and demographic data were collected.Postoperative outcomes were assessed in terms of chest drain bleeding, coagulation profile, blood product requirements, and morbidity within 24 hours. ResultsNo significant difference in chest drain bleeding was observed between the groups.The FFP group showed higher mean arterial pressure during CPB cooling and rewarming.The Non-FFP group required more blood transfusions, while the FFP group maintained a better coagulation profile.