Formulation & Evalution of entric coated tablets of anti- ulcer drugs of Pantaprazole.

Pantoprazole 5-(difluoromethoxy)-2-((3,4-dimethoxypyridin-2-yl) methylsulfinyl)-3H benzoimidazole is a proton pump asset belongs to group of benzimidazole.This emulsion inhabits gastric acid conformation and thereby it's veritably effective for the treatment of gastric and duodenum ulcers.In waterless media more acidic than pH 4 it suffers a virtually complete corruption within a period shorter than 10 twinkles.Indeed, in solid state it's sensitive to heat, moisture, light and especially to substances containing an acidic group.Pantoprazole which has an irritant effect on the stomach, can be carpeted with a substance that will only dissolve in the small intestine.For similar types of medicines, enteric coating added to the expression tends to avoid the stomach's acidic exposure, delivering them rather to a introductory pH terrain (bowel pH 5.5 and over) where they do n't degrade, and give their asked action.This stumulate us to formulate and estimate pantoprazole as a enteric carpeted tablet.