Unlocking the Enigmas of Plasmodium Aspartyl Protease in AntimalarialTherapy: Flap Region Dynamics and Enzyme Repression of Non-Food VacuoleUsing Molecular Dynamics Simulations
Finally, we developed a pharmacophore model based on UCB7362 to offer recommendations for rational drug design of optimized antimalarial drug candidates.
Authors
- Ransford Oduro Kumi (ORCID: https://orcid.org/0009-0002-3274-4285)
- Mahmoud E. S. Soliman
Institutions
- Takoradi Technical University (GH)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-06-02
- DOI
- https://doi.org/10.2174/0113816128288035240130102943
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00