The Importance of Normocapnia in Patients With Severe Traumatic Brain Injury in Prehospital Emergency Medicine

A target PaCO<sub>2</sub> in the lower normal range as early as in the prehospital phase of treatment of patients with severe TBI seems to be associated with a reduced overall 28-day mortality. Our results support the need for a randomized controlled trial of aBGA-guided ventilation in TBI patients in the prehospital setting.

Authors

Jürgen Knapp (ORCID: https://orcid.org/0000-0002-6686-4456)
Martín Müller (ORCID: https://orcid.org/0000-0003-4067-7174)
Urs Pietsch (ORCID: https://orcid.org/0000-0001-6957-2638)
Dominik A. Jakob (ORCID: https://orcid.org/0000-0001-5977-6135)
Wolf E. Hautz (ORCID: https://orcid.org/0000-0002-2445-984X)

Institutions

University of Bern (CH)
University of St.Gallen (CH)
University Hospital of Bern (CH)
Zürich Airport (Switzerland) (CH)

Publication Details

Journal: Journal of the American College of Emergency Physicians Open
Published: 2025-06-03
DOI: https://doi.org/10.1016/j.acepjo.2025.100193
Citations: 2
Primary Topic: Traumatic Brain Injury and Neurovascular Disturbances
Type: article
Field-Weighted Citation Impact: 2.78

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article

The Importance of Normocapnia in Patients With Severe Traumatic Brain Injury in Prehospital Emergency Medicine

Jürgen Knapp, Martín Müller, Urs Pietsch, Dominik A. Jakob et al.

Jun 3, 2025

2 citations

Journal of the American College of Emergency Physicians Open

Traumatic Brain Injury and Neurovascular Disturbances

2.78

article

The Importance of Normocapnia in Patients With Severe Traumatic Brain Injury in Prehospital Emergency Medicine

Jürgen Knapp, Martín Müller, Urs Pietsch, Dominik A. Jakob, Wolf E. Hautz

June 3, 2025article en

2 citations

Abstract

A target PaCO<sub>2</sub> in the lower normal range as early as in the prehospital phase of treatment of patients with severe TBI seems to be associated with a reduced overall 28-day mortality. Our results support the need for a randomized controlled trial of aBGA-guided ventilation in TBI patients in the prehospital setting.

Journal of the American College of Emergency Physicians OpenVol. 6(4)

University of Bern (CH), University of St.Gallen (CH), University Hospital of Bern (CH), Zürich Airport (Switzerland) (CH)

Good health and well-being

Openalex Percentile: Top 10%

Traumatic Brain Injury and Neurovascular Disturbances

2.78

DOI Open Access PDF OpenAlex

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The Importance of Normocapnia in Patients With Severe Traumatic Brain Injury in Prehospital Emergency Medicine — Jürgen Knapp, Martín Müller, et al. · Journal of the American College of Emergency Physicians Open (2025) | TGRS Research Map | TGRS