Cover Feature: Advances in Diclofenac Derivatives: Exploring Carborane‐Substituted <i>N</i>‐Methyl and Nitrile Analogs for Anticancer Therapy (ChemMedChem 11/2025)
Just as spikes help to deter birds from landing on building facades, strategic N-methylation in carborane-substituted diclofenac prevents the carboxylic acid from unwanted lactam formation, thus maintaining the open-chain structure for exploration of its anti-cancer potential. More details can be found in article 10.1002/cmdc.202500084 by Evamarie Hey-Hawkins and co-workers. Art by Christoph Selg.
Authors
- Evamarie Hey‐Hawkins (ORCID: https://orcid.org/0000-0003-4267-0603)
- Tamara Krajnović (ORCID: https://orcid.org/0000-0002-6938-6154)
- Sanja Mijatović (ORCID: https://orcid.org/0000-0001-9509-9098)
- Christoph Selg
- Aleksandr Kazimir (ORCID: https://orcid.org/0000-0001-9037-1638)
- Peter Lönnecke (ORCID: https://orcid.org/0000-0003-1335-0897)
- Markus Laube (ORCID: https://orcid.org/0000-0003-4916-3794)
- Jens Pietzsch (ORCID: https://orcid.org/0000-0002-1610-1493)
- Danijela Maksimović‐Ivanić (ORCID: https://orcid.org/0000-0002-8006-5079)
- Jonas Schädlich (ORCID: https://orcid.org/0009-0002-4550-0394)
- Vuk Gordić (ORCID: https://orcid.org/0009-0006-6382-6063)
- Robert L. Schuster
- Mara Wolniewicz
Institutions
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- Babeș-Bolyai University (RO)
- University of Belgrade (RS)
- Technische Universität Dresden (DE)
- Leipzig University (DE)
Publication Details
- Journal
- ChemMedChem
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1002/cmdc.202581102
- Primary Topic
- Boron Compounds in Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00