Long-Term Follow-Up of Real-World Adjuvant Anti–PD-1 Checkpoint Inhibition and Targeted Therapy in Patients With Stage III Melanoma
PD-1-treated patients with <i>BRAF</i> mutation had a markedly higher rate of relapse compared with TT patients. Rapid recurrences occurred particularly in PD-1-treated patients with previous macroscopic lymph node metastasis. Treatment duration shorter than 6 months did not negatively affect RFS in PD-1, but in TT patients.
Authors
- Bastian Schilling (ORCID: https://orcid.org/0000-0001-8859-4103)
- Julia Huynh (ORCID: https://orcid.org/0000-0002-2357-4184)
- Michael Erdmann (ORCID: https://orcid.org/0000-0001-7136-6489)
- Ralf Gutzmer (ORCID: https://orcid.org/0000-0001-7921-2820)
- Alexander Roesch (ORCID: https://orcid.org/0000-0002-0773-6067)
- Andrea Forschner (ORCID: https://orcid.org/0000-0002-6185-4945)
- Wolfgang Galetzka
- Katharina C. Kähler (ORCID: https://orcid.org/0000-0001-9953-0893)
- Dirk Schadendorf (ORCID: https://orcid.org/0000-0003-3524-7858)
- Friedegund Meier (ORCID: https://orcid.org/0000-0003-4340-9706)
- Georg Christian Lodde (ORCID: https://orcid.org/0000-0002-6930-2694)
- Axel Hauschild (ORCID: https://orcid.org/0000-0002-1212-9587)
- Elisabeth Livingstone (ORCID: https://orcid.org/0000-0001-8279-9239)
- Svea Hüning
- Henner Stege (ORCID: https://orcid.org/0000-0002-2994-7447)
- Carola Berking (ORCID: https://orcid.org/0000-0003-0229-8931)
- Selma Ugurel (ORCID: https://orcid.org/0000-0002-9384-6704)
- Lisa Zimmer (ORCID: https://orcid.org/0000-0002-3680-3521)
- Jessica Cecile Hassel (ORCID: https://orcid.org/0000-0001-7575-6230)
- Lydia Reinhardt (ORCID: https://orcid.org/0000-0001-6232-5132)
- Carmen Loquai
- Valerie Glutsch
- Andreas Stang (ORCID: https://orcid.org/0000-0001-6363-9061)
- Bernd Kowall (ORCID: https://orcid.org/0000-0003-4163-1696)
- Imke von Wasielewski
- Peter Mohr
- Daniel J. Tilkorn
Institutions
- Goethe University Frankfurt (DE)
- German Cancer Research Center (DE)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Christian-Albrechts-Universität zu Kiel (DE)
- Medizinische Hochschule Hannover (DE)
- Humboldt-Universität zu Berlin (DE)
- Institut für Medizinische Informatik, Biometrie und Epidemiologie (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- National Center for Tumor Diseases (DE)
- Essen University Hospital (DE)
- Universitätsklinikum Würzburg (DE)
- Klinikum Dortmund (DE)
- University Hospital Frankfurt (DE)
- Elbe Kliniken Stade-Buxtehude (DE)
- Comprehensive Cancer Center Erlangen (DE)
- Klinikum Bremen-Mitte (DE)
- University Hospital Carl Gustav Carus (DE)
- Johannes Wesling Klinikum Minden (DE)
- Technische Universität Dresden (DE)
- University of Tübingen (DE)
- RWE (Germany) (DE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1200/jco-24-02776
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 4.18