Mathematical modelling of the transmission dynamics of pneumonia and meningitis coinfection with vaccination

Pneumonia and meningitis pose substantial threats to global public health due to their high morbidity and mortality rates. This study investigates the dynamics of these diseases with a focus on coinfection and evaluates the effectiveness of vaccination as a control measure. Using a mathematical model, the transmission dynamics are explored and the basic reproduction number is derived to identify conditions for disease-free and endemic states. Numerical simulations analyze the impact of varying vaccination compliance levels, demonstrating that higher compliance significantly reduces the number of susceptible and infected individuals while increasing the vaccinated population. The study emphasizes the need for integrated public health strategies combining vaccination campaigns, efficient vaccine distribution, and supportive medical care to mitigate the burden of pneumonia and meningitis coinfections. These findings provide a framework for designing effective interventions aimed at reducing disease prevalence and improving public health outcomes.

Authors

Publication Details

Journal
Natural Science and Advanced Technology Education
Published
2025-05-23
DOI
https://doi.org/10.53656/nat2025-1.04
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Mathematical modelling of the transmission dynamics of pneumonia and meningitis coinfection with vaccination

Deborah Danıel, Sefiu Onitilo, Omolade Benjamin, Ayoola Olasunkanmi
Natural Science and Advanced Technology Education
Bacterial Infections and Vaccines
article

Mathematical modelling of the transmission dynamics of pneumonia and meningitis coinfection with vaccination

Deborah Danıel, Sefiu Onitilo, Omolade Benjamin, Ayoola Olasunkanmi
article en

Abstract

Pneumonia and meningitis pose substantial threats to global public health due to their high morbidity and mortality rates. This study investigates the dynamics of these diseases with a focus on coinfection and evaluates the effectiveness of vaccination as a control measure. Using a mathematical model, the transmission dynamics are explored and the basic reproduction number is derived to identify conditions for disease-free and endemic states. Numerical simulations analyze the impact of varying vaccination compliance levels, demonstrating that higher compliance significantly reduces the number of susceptible and infected individuals while increasing the vaccinated population. The study emphasizes the need for integrated public health strategies combining vaccination campaigns, efficient vaccine distribution, and supportive medical care to mitigate the burden of pneumonia and meningitis coinfections. These findings provide a framework for designing effective interventions aimed at reducing disease prevalence and improving public health outcomes.

Natural Science and Advanced Technology EducationVol. 34(1)
Openalex Percentile: Top 88%
Bacterial Infections and Vaccines
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