Immunohistochemical Assessment of Ki-67 in Oral Lichen Planus

Objective: The purpose of the current study was to assess cell proliferation by analyzing the expression of Ki-67 in 30 cases of oral lichen planus (OLP). Material and methods: 30 archival paraffin blocks of OLP were examined for Ki-67 expression using immunohistochemical staining. Normal oral mucosa served as a control. After carefully examining the tissue samples, the number of positive cells was counted in order to semi-quantitatively characterize the expression pattern. Scores ranging from 1 to 3 were assigned to nuclear immunostaining for Ki-67 proliferation. SPSS-13 program was used for the statistical analysis, and p