The uterus is an end organ: a preliminary study of the association between abnormal uterine bleeding and hyperinsulinemia

This study highlights an association between hyperinsulinemia and AUB, with BMI playing a unique role in this relationship. These exploratory findings underscore the need for larger, longitudinal studies to clarify causal mechanisms and evaluate the potential of addressing hyperinsulinemia and BMI as part of AUB prevention and treatment strategies. Limitations, including small sample size and cross-sectional design, should be considered when interpreting these results.

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Publication Details

Journal
Menopause The Journal of The North American Menopause Society
Published
2025-06-03
DOI
https://doi.org/10.1097/gme.0000000000002548
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The uterus is an end organ: a preliminary study of the association between abnormal uterine bleeding and hyperinsulinemia

Gabriela dos Santos, Andrea C. Salcedo, Stephanie Larson, Jane Yun et al.
Menopause The Journal of The North American Menopause Society
Uterine Myomas and Treatments
article

The uterus is an end organ: a preliminary study of the association between abnormal uterine bleeding and hyperinsulinemia

Gabriela dos Santos, Andrea C. Salcedo, Stephanie Larson, Jane Yun, Lani Fox
article en

Abstract

This study highlights an association between hyperinsulinemia and AUB, with BMI playing a unique role in this relationship. These exploratory findings underscore the need for larger, longitudinal studies to clarify causal mechanisms and evaluate the potential of addressing hyperinsulinemia and BMI as part of AUB prevention and treatment strategies. Limitations, including small sample size and cross-sectional design, should be considered when interpreting these results.

Menopause The Journal of The North American Menopause SocietyVol. 32(8)
University of North Carolina at Chapel Hill (US), Loma Linda University Medical Center (US), Loma Linda University (US), Biostatistical Consulting (United States) (US)
Good health and well-being
Openalex Percentile: Top 83%
Uterine Myomas and Treatments
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The uterus is an end organ: a preliminary study of the association between abnormal uterine bleeding and hyperinsulinemia — Gabriela dos Santos, Andrea C. Salcedo, et al. · Menopause The Journal of The North American Menopause Society (2025) | TGRS Research Map | TGRS