Colorectal cancers: descriptive study of 122 cases

Colorectal cancers are a global public health problem and represent the 6th cause of death. Westernization of lifestyle with a diet of animal origin, alcohol consumption, smoking, a sedentary lifestyle leading to overweight and obesity are reported risk factors which can be avoided. The authors report a retrospective, descriptive study over 11 years, in the medical oncology and clinical hematology department of Hopital Principal de Dakar. 122 patients included have colorectal cancer whose diagnosis was histological. The mean age was 52 years old. Sex ratio was 1.4. Clinically, pain was noted in 44 cases. The patients had a preserved general condition classified in 89 cases. Lieberkuhnien adenocarcinoma was found on pathological examination in all patients. According to the TNM classification, the tumor was classified as stage 4 in 55 cases, stage 3 in 44 cases, stage 2 in 17 cases and stage 1 in 9 cases. 83 patients have surgical resection. Surgery was curative in 76 cases and palliative in 7 cases. Adjuvant chemotherapy was performed in 41 cases, and palliative chemotherapy in 73 cases. Evolution was marked by progression in 38 cases, a partial response in 23 cases and stability of the lesions in 10 cases. There were 44 deaths, 26 patients lost to follow-up and 52 patients were alive.