Relationship between sarcopenia and cardiovascular disease among middle-aged and older adults with normal weight in China: functional limitation plays a mediating role
Sarcopenia exerts both direct and indirect effects on incident CVD among middle-aged and older adults who are normal weight, with functional limitation serving as a significant mediator. Interventions targeting both sarcopenia and functional limitation may offer a promising strategy for enhancing cardiovascular health in this population.
Authors
- Zhihui Jia (ORCID: https://orcid.org/0000-0002-5983-9041)
- José Hernández (ORCID: https://orcid.org/0009-0005-1019-1511)
- Yao Jie Xie (ORCID: https://orcid.org/0000-0001-9289-4985)
- Haoxiang Wang (ORCID: https://orcid.org/0000-0002-0361-6527)
- Jiaheng Chen (ORCID: https://orcid.org/0000-0001-9150-4738)
- Hui Cheng (ORCID: https://orcid.org/0000-0003-1535-3979)
Institutions
- Hong Kong Polytechnic University (HK)
- Sun Yat-sen University (CN)
- Chinese University of Hong Kong (HK)
- University of Oxford (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Environmental Health and Preventive Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1265/ehpm.24-00351
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Strong
- National Natural Science Foundation of China
- Peking University
- National Institute on Aging