Approaches to the management of children with lactase deficiency

The article presents review data and results of the authors' own research on modern approaches to the problem of lactase deficiency (LD). Аim - to summarize the literature on modern ideas about the terminology, diagnosis and treatment of LD in children. According to international sources, LD is divided into primary and secondary and can be observed both in childhood and adulthood, which depends on the level of lactase activity. With insufficient enzymatic activity and the use of products containing lactose, such individuals experience various gastrointestinal symptoms. The main approach to the treatment of LD is to limit or completely exclude lactose from the diet until the symptoms disappear. The use of enzyme preparations (lactase) and the use of lactose-free alternative products are also recommended. But cow's milk is an important source of calcium, vitamins and minerals and its complete elimination from the diet without proper compensation can lead to disorders of mineral metabolism, in particular osteopenia and osteoporosis. Therefore, competent diet therapy is a key element in the management of patients with LD. Currently, there is growing interest in the use of lactose-free milk among both children and adults suffering from this pathology. During the study, a dynamic assessment of clinical symptoms was performed in 20 children aged 3-15 years with manifestations of secondary LD against the background of the use of lactose-free milk "Kazkove". A positive effect on the dynamics of clinical symptoms of secondary lactase deficiency was revealed. The authors declare that there is no conflict of interest.