Enhanced engraftment and immunomodulatory effects of integrin alpha-2-overexpressing mesenchymal stromal cells in lipopolysaccharide-induced acute lung injury
ITGA2 creates a favorable microenvironment for MSCs, enhancing their immunomodulatory functions, ultimately offering a promising strategy for MSC-based cell therapy for ALI.
Authors
- Geun-Seup Shin
- Younghyun Lim
- Ok‐Hyeon Kim (ORCID: https://orcid.org/0000-0001-6496-1669)
- Eric L. Chang (ORCID: https://orcid.org/0000-0003-2708-6724)
- Young‐Jin Seo (ORCID: https://orcid.org/0000-0001-8744-8083)
- Jung-Woong Kim (ORCID: https://orcid.org/0000-0003-4458-7213)
- Hana Kang (ORCID: https://orcid.org/0000-0002-9489-8805)
- Jin-Ho Kim (ORCID: https://orcid.org/0000-0001-9524-9981)
- Ji-Young Kim (ORCID: https://orcid.org/0000-0003-3741-6838)
- Hyun Jung Lee (ORCID: https://orcid.org/0000-0002-9941-9826)
- Chul-Hong Kim
Institutions
- Chung-Ang University (KR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1186/s13287-025-04423-1
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Research Foundation
- Ministry of Education
- National Research Foundation of Korea