Rapid identification of a Serratia marcescens outbreak in a neonatal intensive care unit by third-generation long-read nanopore sequencing
Two clonal strains were co-circulating in the NICU setting, with one being the major strain responsible for the outbreak. Rapid molecular characterization with nanopore sequencing confirmed the outbreak. It revealed the phylogenetic relationships among isolates and their antimicrobial potential. This approach enabled effective contextualization of the outbreak and allowed for monitoring its progression.
Authors
- Mireia Urrea
- Martín Iriondo‐Sanz
- Meritxell Cubero (ORCID: https://orcid.org/0000-0001-7648-0686)
- Clàudia Fortuny (ORCID: https://orcid.org/0000-0001-7182-5745)
- Amadeu Gené (ORCID: https://orcid.org/0000-0003-0059-8607)
- Desirée Henares (ORCID: https://orcid.org/0000-0003-2631-2718)
- Iolanda Jordán (ORCID: https://orcid.org/0000-0002-2041-4425)
- Muntsa Rocafort
- Amaresh Pérez-Argüello
- Aleix Lluansí (ORCID: https://orcid.org/0000-0002-2328-6780)
- Carmen Muñoz‐Almagro (ORCID: https://orcid.org/0000-0001-5586-404X)
- Pedro Brotons (ORCID: https://orcid.org/0000-0002-2399-7320)
- Irene Martínez-de-Albéniz
- Alicia Arranz
- Maria Jose Troyano
Institutions
- Hospital Sant Joan de Déu Barcelona (ES)
- Instituto de Salud Carlos III (ES)
- Universitat Internacional de Catalunya (ES)
- Sant Joan de Déu Research Foundation (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Antimicrobial Resistance and Infection Control
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1186/s13756-025-01582-x
- Citations
- 5
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 6.59