Potential regulatory mechanism of overexpression of phosphatidylinositol glycan anchor biosynthesis class U on the glycolytic pathway in hepatocellular carcinoma
Overexpression of PIGU may potentially promote glycolysis by regulating the conversion from Glucose to G6P and from 3PD to Pyruvate, affecting the cell cycle, and thereby promoting the occurrence and development of HCC.
Authors
- Rong‐Quan He (ORCID: https://orcid.org/0000-0002-7752-2080)
- Yuxing Tang (ORCID: https://orcid.org/0000-0002-6452-2751)
- Jian‐Di Li (ORCID: https://orcid.org/0000-0001-7050-371X)
- Yi‐Wu Dang (ORCID: https://orcid.org/0000-0002-7793-1239)
- Huijun Li (ORCID: https://orcid.org/0000-0002-2896-3867)
- Gang Chen (ORCID: https://orcid.org/0000-0002-8320-6594)
- Shengsheng Zhou
- Wan-Ying Huang (ORCID: https://orcid.org/0000-0002-8314-5963)
- Dandan Xiong (ORCID: https://orcid.org/0000-0002-5362-0938)
- Bang‐Teng Chi (ORCID: https://orcid.org/0009-0000-5504-5589)
- Yu-Long Deng (ORCID: https://orcid.org/0009-0005-5314-2576)
Institutions
- Guangxi Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- Gene
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1016/j.gene.2025.149603
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00