Heart Transplantation in post-infarction ventricular septal rupture: Contemporary outcomes from the 2016-2021 National Inpatient Database
From 2016 to 2021, among VSR-CS admissions in the United States, patients who underwent HT had no in-hospital mortality, in contrast to the high in-hospital-mortality observed with surgical or transcatheter closure. Despite inherent selection biases, including survival to transplantation, HT was associated with favorable outcomes compared to surgical repair. While promising, these findings are preliminary due to the small sample size and selective nature of the patient cohort. Further studies are required before HT can be broadly recommended as a primary treatment option.
Authors
- Mazen Albaghdadi (ORCID: https://orcid.org/0000-0003-2369-0967)
- Luis H. Paz Rios (ORCID: https://orcid.org/0000-0001-7024-8990)
- Wael Dakkak
- Travis Howard (ORCID: https://orcid.org/0000-0001-8765-9964)
- Dhiran Verghese (ORCID: https://orcid.org/0000-0003-1904-7397)
- Dee Dee Wang (ORCID: https://orcid.org/0000-0002-5784-9924)
- Robert J. Cubeddu
- Carl E. Orringer
- Dániel Hanna (ORCID: https://orcid.org/0000-0002-5068-5402)
- Juan Carlos Sierra (ORCID: https://orcid.org/0000-0002-5593-9803)
- Viviana Navas
Institutions
- Naples Community Hospital Healthcare System (US)
- Edwards Lifesciences (United States) (US)
- Edwards Lifesciences (Switzerland) (CH)
Publication Details
- Journal
- JHLT Open
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1016/j.jhlto.2025.100278
- Primary Topic
- Cardiac Structural Anomalies and Repair
- Type
- article
- Field-Weighted Citation Impact
- 0.00