Factors Associated with Complete HPV Vaccination Among Girls Aged 11-13 Years in Diakhao Health District in 2021

<i>Introduction:</i> In 2021, (88.6%) of Senegal's 79 districts had not reached the full Human papillomavirus (HPV) vaccination coverage target of (90%). The Diakhao health district had full vaccination coverage of (10%) in the same year. This study aimed to identify factors associated with full vaccination coverage among girls aged 11-13 in Diakhao health district. <i>Method:</i> This was a descriptive and analytical study conducted in Diakhao health district among 228 custodial mothers of young girls aged 11-13 years. Data were collected using a questionnaire assessing the knowledge, attitudes, practices, and satisfaction of custodial mothers of young girls aged 11-13 years about HPV vaccination. Descriptive, bivariate analysis, and logistic regression were performed at 5% alpha. <i>Results:</i> The majority (74.12%) of mothers and guardians had heard of cervical cancer, and 81.58% had heard of HPV vaccination. According to the mothers and guardians of young girls, there was complete coverage (17.54%). According to the vaccination card, complete coverage was (15.79%). Factors associated with complete coverage were: the girl's schooling (ORa = 3.56 (1.12-11.29); having heard about cervical cancer vaccination (ORa = 0.09 (0.02, 0.32)]); rural residence (ORa = 0.13 (0.04-0. 44); agreement with vaccination for reasons of protection against certain communicable diseases (ORa = 8.95 (1.27-63.11) or reasons of vaccination of neighbors' children (ORa = 3.25 (1.24-8.55), satisfaction with counseling (ORa = 6.49 (1.63-25.8). <i>Conclusion:</i> Information to mothers or guardians of young girls is crucial to achieving the goal of full immunization coverage. It could be significantly improved by an acceleration plan focusing on interpersonal communication.