SREBP1 deficiency aggravates vascular calcification via iASPP-triggered ferroptosis of vascular smooth muscle cells
These findings report that targeting SREBP1 or iASPP may represent an attractive interventional strategy for VC in CKD.
Authors
- Laura Harrell ve Eugene B. Chang
- Yunhui Wu
- Yaling Bai
- Haoqi Sun (ORCID: https://orcid.org/0000-0002-5041-8312)
- Dongxue Zhang (ORCID: https://orcid.org/0000-0002-5714-7893)
- Jinsheng Xu
- Binbin Yang (ORCID: https://orcid.org/0000-0002-8211-0830)
- Jingjing Jin (ORCID: https://orcid.org/0009-0002-3159-0990)
- Meijuan Cheng
- Shenglei Zhang (ORCID: https://orcid.org/0000-0002-1544-964X)
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1186/s12933-025-02797-3
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- Natural Science Foundation of Hebei Province