Assessing Occlusion and Recovery in Large and Giant Intracranial Aneurysms: A Comparative Retrospective Study of Flow Diversion Alone Versus Combined With Coiling and the Role of Packing Density
In this study, FD with minimal coiling at a PD of 12% to 14% significantly enhanced complete aneurysm occlusion and functional recovery in patients with large aneurysms compared with using FD alone. PD above 12% to 14% threshold up to 26% impact on occlusion rates is particularly pronounced in very large or giant aneurysms.
Authors
- Zachary Hubbard (ORCID: https://orcid.org/0000-0002-5643-9480)
- Conor Cunningham (ORCID: https://orcid.org/0000-0002-2628-4828)
- Alejandro M Spiotta (ORCID: https://orcid.org/0000-0002-7142-5538)
- Jaims Lim (ORCID: https://orcid.org/0000-0002-9847-3601)
- Ariana Chacón (ORCID: https://orcid.org/0000-0003-2005-5781)
- Emmanuel Mensah (ORCID: https://orcid.org/0000-0002-4644-8674)
- Rahim Abo Kasem (ORCID: https://orcid.org/0000-0002-9635-7471)
- Vinay Jaikumar (ORCID: https://orcid.org/0000-0002-6677-1858)
- Mohammad‐Mahdi Sowlat (ORCID: https://orcid.org/0000-0001-6777-4332)
- Bernard Okai (ORCID: https://orcid.org/0009-0005-9890-8272)
- Joshua M. Venegas (ORCID: https://orcid.org/0009-0007-6926-1339)
- Hasna Loulida (ORCID: https://orcid.org/0009-0002-2641-8432)
- Adnan Siddiqui
Institutions
- Beth Israel Deaconess Medical Center (US)
- Kaleida Health (US)
- Medical University of South Carolina (US)
- Jacobs (United States) (US)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1227/neu.0000000000003546
- Citations
- 3
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 4.17