Muscone Reduces OGD/R-Induced Hyperpermeability of the Brain Endothelial Barrier by Activating the PKA/RHOA/MLC Pathway

We demonstrated that muscone could reduce OGD/R-induced hyperpermeability of the brain endothelial barrier by activating the PKA/RHOA/MLC pathway.

Authors

Guangyun Wang
Yunxia Zuo (ORCID: https://orcid.org/0000-0002-3539-5706)
Ziteng Yang
Ning Wang (ORCID: https://orcid.org/0009-0002-2976-6846)

Institutions

Anhui University of Traditional Chinese Medicine (CN)

Publication Details

Journal: Current Neurovascular Research
Published: 2025-01-01
DOI: https://doi.org/10.2174/0115672026377602250520063326
Primary Topic: Flavonoids in Medical Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Muscone Reduces OGD/R-Induced Hyperpermeability of the Brain Endothelial Barrier by Activating the PKA/RHOA/MLC Pathway

Guangyun Wang, Yunxia Zuo, Ziteng Yang, Ning Wang

Jan 1, 2025

Current Neurovascular Research

Flavonoids in Medical Research

article

Muscone Reduces OGD/R-Induced Hyperpermeability of the Brain Endothelial Barrier by Activating the PKA/RHOA/MLC Pathway

Guangyun Wang, Yunxia Zuo, Ziteng Yang, Ning Wang

January 1, 2025article en

Abstract

We demonstrated that muscone could reduce OGD/R-induced hyperpermeability of the brain endothelial barrier by activating the PKA/RHOA/MLC pathway.

Current Neurovascular ResearchVol. 22(1)

Anhui University of Traditional Chinese Medicine (CN)

Openalex Percentile: Top 86%

Flavonoids in Medical Research

DOI Source OpenAlex

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Muscone Reduces OGD/R-Induced Hyperpermeability of the Brain Endothelial Barrier by Activating the PKA/RHOA/MLC Pathway — Guangyun Wang, Yunxia Zuo, et al. · Current Neurovascular Research (2025) | TGRS Research Map | TGRS