EVALUATING THE SYNERGISTIC AND ANTIBACTERIAL EFFECTS OF FRESHWATER PLANTS AND SEAGRASS EXTRACTS ON ACINETOBACTER BAUMANNII

Acinetobacter baumannii has become one of the most dangerous global health pathogens in nosocomial infections, exhibiting increasing resistance to a wide range of antimicrobial agents.This resistance presents challenges in treatment and highlights the pressing need for innovative approaches to address these infections.Therefore, our investigation focuses on the ability of extracts produced from specific freshwater plants and seagrasses to inhibit the growth of A. baumannii.Moreover, we explore the potential synergistic effects of these natural extracts when used together with certain antibiotics.Our study evaluates the synergistic antibacterial effects between these extracts and antibiotics via the agar diffusion assay.The results showed that extracts from some species of freshwater plants were more effective in inhibiting the growth of A. baumannii than extracts from seagrasses.The variation in effectiveness is due to the solvents used for extraction and their differing capabilities.It is well known that A. baumannii has an inherent resistance to various classes of antibiotics, but this study also showed that certain plant extracts had substantial synergistic effects against the tested pathogenic microbe.This work demonstrates the potential of natural plant extracts as a complementary adjunct options to standard antibiotic therapy.