A white matter-centered approach to investigate recurrence pathways in high-grade gliomas: a single-center retrospective study
Our analysis, focused on exploring the spatial aspects of recurrence in relation to white matter anatomy, suggests that HGG recurrence patterns are strongly influenced by anatomical location and white matter architecture. Certain anatomical areas show a predisposition toward specific recurrence patterns. Recognizing these spatial dynamics may guide more precise surgical strategies, radiotherapy targeting, and recurrence risk assessment.
Authors
- Lucia Di Maio
- Grazia Menna (ORCID: https://orcid.org/0000-0003-2594-4967)
- Pier Paolo Mattogno (ORCID: https://orcid.org/0000-0003-2857-9096)
- Simona Gaudino (ORCID: https://orcid.org/0000-0003-1681-4343)
- Rosellina Russo (ORCID: https://orcid.org/0000-0002-1791-5085)
- Alessandro Olivi (ORCID: https://orcid.org/0000-0002-4489-7564)
- Naike Caraglia
- Liverana Lauretti (ORCID: https://orcid.org/0000-0002-6463-055X)
- Francesco Doglietto (ORCID: https://orcid.org/0000-0002-7438-0734)
- Davide Quaranta (ORCID: https://orcid.org/0000-0003-2905-6625)
- Silvia Chiesa (ORCID: https://orcid.org/0000-0003-0168-3459)
- Giuseppe Maria Della Pepa (ORCID: https://orcid.org/0000-0001-8698-3359)
- Quintino Giorgio D’Alessandris (ORCID: https://orcid.org/0000-0002-2953-9291)
- Rina Di Bonaventura (ORCID: https://orcid.org/0000-0001-5065-430X)
- Marco Galeazzi (ORCID: https://orcid.org/0009-0000-4020-8883)
- Salvatore Marino (ORCID: https://orcid.org/0000-0003-2968-9713)
- Gianmaria Marziali
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Cambia (AU)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1007/s11060-025-05050-9
- Citations
- 3
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- Università Cattolica del Sacro Cuore