Targeting NLRP3 signaling with a novel sulfonylurea compound for the treatment of vascular cognitive impairment and dementia

Authors

Adnan Akif (ORCID: https://orcid.org/0000-0003-1364-4377)
Yang Zhang (ORCID: https://orcid.org/0000-0002-8338-3013)
Amol A. Kulkarni (ORCID: https://orcid.org/0000-0002-9395-9338)
Langni Liu (ORCID: https://orcid.org/0000-0001-8069-6711)
Jianxiong Jiang (ORCID: https://orcid.org/0000-0003-3955-8928)
Jiukuan Hao (ORCID: https://orcid.org/0000-0002-4483-183X)
T.T. Nguyen (ORCID: https://orcid.org/0009-0007-5946-3551)
Xiaotian Xu (ORCID: https://orcid.org/0000-0003-3862-1630)

Institutions

University of Tennessee Health Science Center (US)
The University of Texas at El Paso (US)
Northern Jiangsu People's Hospital (CN)
Institute of Neuroimmunology of the Slovak Academy of Sciences (SK)
University of Houston (US)
Yangzhou University (CN)
The University of Texas Health Science Center at Houston (US)

Publication Details

Journal: Fluids and Barriers of the CNS
Published: 2025-06-03
DOI: https://doi.org/10.1186/s12987-025-00665-6
Citations: 5
Primary Topic: Neurological Disease Mechanisms and Treatments
Type: article
Field-Weighted Citation Impact: 4.21

Funders

National Institutes of Health
National Institute of Neurological Disorders and Stroke

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article

Targeting NLRP3 signaling with a novel sulfonylurea compound for the treatment of vascular cognitive impairment and dementia

Adnan Akif, Yang Zhang, Amol A. Kulkarni, Langni Liu et al.

Jun 3, 2025

5 citations

Fluids and Barriers of the CNS

Neurological Disease Mechanisms and Treatments

4.21

article

Targeting NLRP3 signaling with a novel sulfonylurea compound for the treatment of vascular cognitive impairment and dementia

Adnan Akif, Yang Zhang, Amol A. Kulkarni, Langni Liu, Jianxiong Jiang, Jiukuan Hao, T.T. Nguyen, Xiaotian Xu

June 3, 2025article en

5 citations

Abstract

No abstract available for this paper.

Fluids and Barriers of the CNSVol. 22(1)

University of Tennessee Health Science Center (US), The University of Texas at El Paso (US), Northern Jiangsu People's Hospital (CN), Institute of Neuroimmunology of the Slovak Academy of Sciences (SK), University of Houston (US), Yangzhou University (CN), The University of Texas Health Science Center at Houston (US)

National Institutes of Health, National Institute of Neurological Disorders and Stroke

Openalex Percentile: Top 6%

Neurological Disease Mechanisms and Treatments

4.21

DOI Open Access PDF OpenAlex

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