Central adiposity indices and inflammatory markers mediate the association between life’s crucial 9 and periodontitis in US adults
Higher LC9 score is linked to reduced periodontitis prevalence and severity, with central adiposity and systemic inflammation partially mediating this relationship. These findings emphasize comprehensive cardiovascular health management may help reduce periodontal disease risk.
Authors
- Jing Zhang (ORCID: https://orcid.org/0000-0002-1796-6042)
- Zhuang Tian (ORCID: https://orcid.org/0000-0003-1140-4062)
- Qi-Qi Hang (ORCID: https://orcid.org/0009-0009-9661-8609)
- Ting Xu (ORCID: https://orcid.org/0000-0002-1532-1494)
- Hanlin Ou (ORCID: https://orcid.org/0000-0001-8140-9585)
- Xueshan Qiu (ORCID: https://orcid.org/0000-0001-9481-8249)
- Jing‐Yun Gao
- Wang Liang (ORCID: https://orcid.org/0009-0008-2004-2968)
- Yu‐Zhong Zhang (ORCID: https://orcid.org/0000-0002-2017-1005)
- Jiajie Guo (ORCID: https://orcid.org/0000-0002-4116-6512)
- Fengwei Jiang (ORCID: https://orcid.org/0000-0001-7407-0464)
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Chinese University of Hong Kong, Shenzhen (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Shenzhen University Health Science Center (CN)
- Community Health Center (US)
- Hangzhou Dianzi University (CN)
- Nanjing Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-06-03
- DOI
- https://doi.org/10.1186/s12944-025-02619-1
- Citations
- 8
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 14.54