Partial adrenalectomy for pheochromocytoma in the multiple endocrine neoplasia type 2 population: Time to reconsider?

These data show that there is a considerable risk of ipsilateral recurrent disease in the short term after partial adrenalectomy for multiple endocrine neoplasia type 2-related pheochromocytoma with a 50% chance of adrenal insufficiency in cases of bilateral surgery. Therefore, we doubt whether partial adrenalectomy should be preferred for multiple endocrine neoplasia type 2-associated pheochromocytoma. We propose total adrenalectomy as the standard technique and partial adrenalectomy only for selected cases.

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Publication Details

Journal
Surgery
Published
2025-06-03
DOI
https://doi.org/10.1016/j.surg.2025.109452
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
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article

Partial adrenalectomy for pheochromocytoma in the multiple endocrine neoplasia type 2 population: Time to reconsider?

Tessa M. van Ginhoven, Gerlof D. Valk, Richard Abraham Feelders, Charlotte L. Viëtor et al.
Surgery
Adrenal and Paraganglionic Tumors
article

Partial adrenalectomy for pheochromocytoma in the multiple endocrine neoplasia type 2 population: Time to reconsider?

Tessa M. van Ginhoven, Gerlof D. Valk, Richard Abraham Feelders, Charlotte L. Viëtor, Diederik P.D. Suurd, Inne H.M. Borel Rinkes, Medard F. M. van den Broek, Menno R. Vriens
article en

Abstract

These data show that there is a considerable risk of ipsilateral recurrent disease in the short term after partial adrenalectomy for multiple endocrine neoplasia type 2-related pheochromocytoma with a 50% chance of adrenal insufficiency in cases of bilateral surgery. Therefore, we doubt whether partial adrenalectomy should be preferred for multiple endocrine neoplasia type 2-associated pheochromocytoma. We propose total adrenalectomy as the standard technique and partial adrenalectomy only for selected cases.

SurgeryVol. 184
Erasmus MC (NL), University Medical Center Utrecht (NL)
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Openalex Percentile: Top 78%
Adrenal and Paraganglionic Tumors
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Partial adrenalectomy for pheochromocytoma in the multiple endocrine neoplasia type 2 population: Time to reconsider? — Tessa M. van Ginhoven, Gerlof D. Valk, et al. · Surgery (2025) | TGRS Research Map | TGRS