Vasospastic Angina Confirmed by Nitrate Challenge: A Case Report

A 61-year-old male smoker with hypertension presented with exertional chest pain and minor troponin elevation. ECG showed apico-lateral T wave inversions. A positive stress test led to coronary angiography, which revealed a subocclusion of the right coronary artery. After intracoronary nitrate injection, the lesion resolved completely, confirming coronary artery spasm. Vasospastic angina remains an underdiagnosed cause of chest pain and can mimic fixed coronary lesions, potentially leading to unnecessary interventions. Smoking is a key risk factor, and nitrate responsiveness is critical for diagnosis. This case highlights the importance of recognizing functional coronary obstruction and the role of nitrates in avoiding misdiagnosis.

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Publication Details

Journal
Scholars Journal of Medical Case Reports
Published
2025-05-21
DOI
https://doi.org/10.36347/sjmcr.2025.v13i05.079
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Vasospastic Angina Confirmed by Nitrate Challenge: A Case Report

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Scholars Journal of Medical Case Reports
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Vasospastic Angina Confirmed by Nitrate Challenge: A Case Report

Hicham Faliouni, Youssef Fihri, Mohamed Laaroussi, Zouhair Lakhal, Aatif Benyass, Nabil Laktib, Driss Britel, Soumia Faid, Donatien Mukeba Ntite
article en

Abstract

A 61-year-old male smoker with hypertension presented with exertional chest pain and minor troponin elevation. ECG showed apico-lateral T wave inversions. A positive stress test led to coronary angiography, which revealed a subocclusion of the right coronary artery. After intracoronary nitrate injection, the lesion resolved completely, confirming coronary artery spasm. Vasospastic angina remains an underdiagnosed cause of chest pain and can mimic fixed coronary lesions, potentially leading to unnecessary interventions. Smoking is a key risk factor, and nitrate responsiveness is critical for diagnosis. This case highlights the importance of recognizing functional coronary obstruction and the role of nitrates in avoiding misdiagnosis.

Scholars Journal of Medical Case ReportsVol. 13(05)
Openalex Percentile: Top 79%
Cerebrovascular and Carotid Artery Diseases
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