Stimulation of bone tissue regeneration in osteoporotic fractures of the proximal femur. Literature review

Abstract The article is devoted to the study of methods for stimulating bone tissue regeneration in proximal femur fractures (PFF) in elderly and senile patients, since the issue of timing and quality of fracture consolidation and the possibility of activation in the studied age group is quite relevant. The literature review is based on Russian-language and foreign primary sources from 2010 to 2022, which describe various methods for stimulating bone tissue regeneration. In this regard, the authors conduct an analysis of the literature, which allows identifying the most promising method at this stage. Objective. Analysis of existing methods for stimulating bone tissue regeneration in proximal femur fractures against the background of osteoporosis in elderly patients. At this stage of clinical practice, there are many methods for stimulating bone tissue regeneration, both labor-intensive and costly, and highly effective and easy to perform. Each of the treatment methods has both positive and negative features. Based on the analysis, it was concluded that bone marrow cells injected directly into the fracture zone have high efficiency in stimulating bone tissue regeneration, however, to optimize this method, further improvement of the technology for collecting and preparing stem cells is required.