Association between D-dimer and in-hospital mortality risk in Acute Kidney Injury based on latent class dynamic trajectory

Using LCTM analysis, it was determined that D-dimer exhibits two characteristic longitudinal dynamic trajectories following AKI onset: an early peak followed by a gradual decline and a continuous low-level stability. Among these, the trajectory characterized by an early peak followed by a decline in AKI patients was associated with an increased risk of in-hospital mortality and reduced in-hospital survival, independent of age, gender, chronic kidney disease, cancer, surgery, myocardial infarction, or cerebral infarction.