Adenosquamous Carcinoma of the Gallbladder: A Case Report of a Locally Advanced Carcinoma With a Positive Outcome

We report a rare case of adenosquamous carcinoma of the gallbladder. The patient presented with unexplained weight loss and a palpable mass below the right costal margin. A computed tomography (CT) scan suggested gallbladder carcinoma, prompting radical surgery. Histological assessment confirmed adenosquamous carcinoma of the gallbladder. Although resection margins were negative (R0), peritumoral lymph node metastases were identified. The patient subsequently received adjuvant chemotherapy with capecitabine, as recommended by a multidisciplinary tumor board (MDT). Six-month follow-up imaging showed no evidence of metastasis or recurrence.

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Journal
Cureus
Published
2025-06-02
DOI
https://doi.org/10.7759/cureus.85218
Citations
1
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
2.01
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article

Adenosquamous Carcinoma of the Gallbladder: A Case Report of a Locally Advanced Carcinoma With a Positive Outcome

Julia Michel, Jens Hoeppner, K. Nowakowski, Zsolt Madarasz et al.
1 citations
Cureus
Cholangiocarcinoma and Gallbladder Cancer Studies
2.01
article

Adenosquamous Carcinoma of the Gallbladder: A Case Report of a Locally Advanced Carcinoma With a Positive Outcome

Julia Michel, Jens Hoeppner, K. Nowakowski, Zsolt Madarasz, Felix Hilderbrandt
article en
1 citations

Abstract

We report a rare case of adenosquamous carcinoma of the gallbladder. The patient presented with unexplained weight loss and a palpable mass below the right costal margin. A computed tomography (CT) scan suggested gallbladder carcinoma, prompting radical surgery. Histological assessment confirmed adenosquamous carcinoma of the gallbladder. Although resection margins were negative (R0), peritumoral lymph node metastases were identified. The patient subsequently received adjuvant chemotherapy with capecitabine, as recommended by a multidisciplinary tumor board (MDT). Six-month follow-up imaging showed no evidence of metastasis or recurrence.

CureusVol. 17(6)
Klinikum Lippe (DE), Klinikum Bielefeld (DE)
Good health and well-being
Openalex Percentile: Top 15%
Cholangiocarcinoma and Gallbladder Cancer Studies
2.01
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