L-Citrulline Improves IGF-1 Signaling Pathway in Preeclampsia via Polyamines
L-citrulline supplementation improves the IGF-1 signaling pathway in preeclampsia, at least partly, via polyamine production. Maternal supplementation with L-citrulline or polyamine may represent a safe and effective therapeutic strategy for preeclampsia.
Authors
- Joscha Steetskamp (ORCID: https://orcid.org/0000-0002-2928-8461)
- Annette Hasenburg (ORCID: https://orcid.org/0000-0002-1547-4968)
- Andy W. C. Man (ORCID: https://orcid.org/0000-0002-4113-6479)
- Gisela Reifenberg
- Andreas Daiber (ORCID: https://orcid.org/0000-0002-2769-0094)
- Huige Li (ORCID: https://orcid.org/0000-0003-3458-7391)
- Josche van der Ven
- Ning Xia (ORCID: https://orcid.org/0000-0002-5553-1752)
Institutions
- Johannes Gutenberg University Mainz (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- German Centre for Cardiovascular Research (DE)
Publication Details
- Journal
- Hypertension
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1161/hypertensionaha.125.24785
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 2.06