Wilkie Syndrome Complicating Peptic Ulcer-Related Stenosis: A Unique Clinical Case

Peptic ulcers are a leading cause of gastric outlet obstruction, with endoscopic treatment combined with medical therapy for Helicobacter pylori infection being the gold standard. Weight loss is one of the major complications of gastric outlet obstruction. Authors presented the case of a patient who experienced chronic gastric pain, vomiting and weight loss. The initial oesophagogastroduodenoscopy (EGD) revealed peptic ulcer stenosis and the presence of H. pylori. Although medical treatment was initiated, there was no significant improvement. Further investigation using an abdominal CT scan revealed the development of superior mesenteric artery syndrome, which required surgical intervention. This case highlights the potential complications of H. pylori infection, particularly weight loss, and emphasizes the possibility of progression to superior mesenteric artery syndrome.