Cover Feature: Supramolecular Polymers of Amino Triazines vs. Amino Pyrimidines in Aqueous Solution: How Key Interactions Control their Thermodynamic Stability (Chem. Asian J. 10/2025)

The cover illustrates the behavior of two supramolecular systems derived from aminotriazine (AT) and aminopyrimidine (AP) moieties in the presence of water and sodium cations. As demonstrated by our molecular dynamics analyses, the AT-based system remains stable in aqueous solution, whereas the AP-based system undergoes complete disassembly. Additional computational experiments suggest that the stability of the latter could be modulated by adjusting the pH or through charge screening effects. More details can be found in article number e202401905 by Andre N. Petelski and co-workers.