Quercetin Protects against Ethanol-induced Neurodegeneration in Adult Rat Cortex
Immunohistological findings i.e. caspase-3 immunoreactivity, Nissl staining, and Fluoro- Jade B staining also revealed significant neuronal survival with quercetin treatment against ethanol- induced neuronal cell death. Our in-silico and in-vivo findings suggest that quercetin has the potential capability to be used as a neuroprotective agent against alcoholic neurotoxicity.
Authors
- Haroon Badshah (ORCID: https://orcid.org/0000-0003-2959-0414)
- Heeyoung Kang (ORCID: https://orcid.org/0000-0001-5404-1674)
- Rehman Zafar (ORCID: https://orcid.org/0000-0003-2560-9384)
- Myeong Ok Kim (ORCID: https://orcid.org/0000-0003-4317-1072)
- Sangbae Ma
- Haroon Khan (ORCID: https://orcid.org/0000-0003-0895-0396)
Institutions
- Abdul Wali Khan University Mardan (PK)
- Gyeongsang National University (KR)
- Riphah International University (PK)
- Korea University (KR)
- Gyeongsang National University Hospital (KR)
- Convergence Research Center for Diagnosis Treatment and Care System of Dementia (KR)
- Gyeonggi Research Institute (KR)
Publication Details
- Journal
- Current Neuropharmacology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.2174/011570159x349349250118152027
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Ministry of Science and ICT, South Korea