Effects of semaglutide on metabolism and gut microbiota in high-fat diet-induced obese mice
In summary, semaglutide could inhibit food intake and improve obesity, regulate serum metabolism and the composition of gut microbiota in mice. Bacterial transplantation is key to transmitting the improvement brought about by fecal microbiota transplantation of semaglutide to recipient mice.
Authors
- Guolong Liu (ORCID: https://orcid.org/0000-0002-8336-1703)
- Bin Shang (ORCID: https://orcid.org/0000-0002-5582-2293)
- Suyuan Lv (ORCID: https://orcid.org/0000-0001-6656-371X)
- Luyan Sun
- Wu Qiu
- Yue Geng
Institutions
- Shandong Normal University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.3389/fphar.2025.1562896
- Citations
- 10
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 11.64