Berbamine inhibits cell proliferation and invasion by increasing FTO expression in renal cell carcinoma cells
Collectively, our findings revealed that targeting the tumor suppressive FTO by BBM is a new option to inhibit RCC cells growth and metastasis, providing a good drug candidate potential for development novel therapeutics against metastatic RCC.
Authors
- Lixiong Shuai
- Lifeng Deng
- Jingze Xu
- Xinyang Cheng
- Mengmeng Xu (ORCID: https://orcid.org/0000-0001-6699-4499)
- Yongsheng Zhang (ORCID: https://orcid.org/0000-0001-8201-1659)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-5843-8705)
- Tianyu Yang (ORCID: https://orcid.org/0000-0002-0283-846X)
Institutions
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1186/s12885-025-13463-y
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China