Tarlatamab in Small-Cell Lung Cancer after Platinum-Based Chemotherapy
Treatment with tarlatamab led to longer overall survival than chemotherapy among patients with small-cell lung cancer whose disease had progressed during or after platinum-based chemotherapy. (Funded by Amgen; DeLLphi-304 ClinicalTrials.gov number, NCT05740566.).
Authors
- Longhua Sun (ORCID: https://orcid.org/0009-0009-7964-5699)
- Tudor–Eliade Ciuleanu (ORCID: https://orcid.org/0000-0003-0958-5597)
- Bo Zhu (ORCID: https://orcid.org/0000-0002-5829-9581)
- Taofeek K. Owonikoko (ORCID: https://orcid.org/0000-0002-7724-7728)
- Sofia Baka
- Sally C. M. Lau (ORCID: https://orcid.org/0000-0001-9217-2368)
- Ji‐Youn Han (ORCID: https://orcid.org/0000-0001-5033-0006)
- Mahmut Gümüş (ORCID: https://orcid.org/0009-0001-7894-2319)
- Myung‐Ju Ahn (ORCID: https://orcid.org/0000-0002-5740-9654)
- Martin Schüler (ORCID: https://orcid.org/0000-0002-2166-3394)
- Giannis Mountzios (ORCID: https://orcid.org/0000-0002-7780-7836)
- Pedro Rocha (ORCID: https://orcid.org/0000-0003-3221-7354)
- Charles M. Rudin (ORCID: https://orcid.org/0000-0001-5204-3465)
- Luis Paz‐Ares (ORCID: https://orcid.org/0000-0002-1947-3364)
- Julien Mazières (ORCID: https://orcid.org/0000-0002-5921-7613)
- Umut Demırcı (ORCID: https://orcid.org/0000-0002-4833-6721)
- Byoung Chul Cho (ORCID: https://orcid.org/0000-0002-5562-270X)
- Ali Hamidi (ORCID: https://orcid.org/0000-0002-1096-5119)
- Diana Maria Gauto
- Antonio Lugini
- Yan Yu (ORCID: https://orcid.org/0000-0002-8840-9497)
- Tatsuya Yoshida (ORCID: https://orcid.org/0000-0003-4896-5824)
- Fiona Helen Blackhall (ORCID: https://orcid.org/0000-0001-8716-3395)
- Tony Jiang (ORCID: https://orcid.org/0000-0001-8867-9385)
- Ippokratis Korantzis
- Gonzálo Recondo (ORCID: https://orcid.org/0000-0002-4755-9325)
Institutions
- Hebron University (PS)
- University of Maryland, Baltimore (US)
- Amgen (United States) (US)
- Memorial Sloan Kettering Cancer Center (US)
- Université Toulouse III - Paul Sabatier (FR)
- Nanchang University (CN)
- Army Medical University (CN)
- Harbin Medical University (CN)
- Dalian Medical University (CN)
- Yonsei University (KR)
- Azienda Ospedaliera San Giovanni Addolorata (IT)
- Interbalkan Medical Center (GR)
- Samsung Medical Center (KR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- NYU Langone Health (US)
- National Cancer Center (US)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Memorial Ankara Hospital (TR)
- Institute of Oncology Prof. Dr. Ion Chiricuta (RO)
- Hospital Universitario 12 De Octubre (ES)
- St. Luke's Hospital (GR)
- Third Affiliated Hospital of Harbin Medical University (CN)
- National Center for Tumor Diseases (DE)
- Essen University Hospital (DE)
- National Cancer Center (KR)
- The Christie NHS Foundation Trust (GB)
- Henry Dunant Hospital (GR)
- First Affiliated Hospital of Nanchang University (CN)
- Vall d'Hebron Institute of Oncology (ES)
- NYU Langone’s Laura and Isaac Perlmutter Cancer Center
- University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center
- Istanbul Medeniyet University (TR)
- Sungkyunkwan University (KR)
- Chongqing Medical University (CN)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1056/nejmoa2502099
- Citations
- 113
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 118.13
Funders
- Amgen