A Unified Strategy for Transition-Metal-Free Synthesis of Benzothienopyridines, Benzoselenopyridines, and Benzotelluropyridines and Related Analogues
A transition-metal-free, unified synthetic approach has been developed for the efficient construction of benzothienopyridines, benzoselenopyridines, and benzotelluropyridines. This versatile methodology facilitates the formation of C-S, C-Se, and C-Te bonds through the cyclization reaction of readily available dihalogenated pyridyl biaryls with chalcogen sources (thiourea, elemental sulfur, selenium, or tellurium). Significantly, the derivatized products exhibit promising potential as building blocks for benzochalcogenophene-fused pyridine architectures and functional materials for organic optoelectronic applications, particularly in organic light-emitting diodes.
Authors
- Tie‐Gen Chen (ORCID: https://orcid.org/0000-0001-6555-5099)
- Xiang Zheng (ORCID: https://orcid.org/0000-0002-1880-650X)
- Jianlian Wu
- Zhaoyue Wen
- Chun Wang (ORCID: https://orcid.org/0000-0002-9366-3668)
- Chang Lu (ORCID: https://orcid.org/0000-0003-0181-5888)
- Wei Chen (ORCID: https://orcid.org/0000-0002-2282-0769)
- Bingjie Shen (ORCID: https://orcid.org/0009-0007-5293-1404)
- Mingyue Fu
Institutions
- Chinese Academy of Sciences (CN)
- Hong Kong University of Science and Technology (HK)
- Shanghai Institute of Materia Medica (CN)
- Southwest Jiaotong University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1021/acs.orglett.5c01557
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- Shanghai Rising-Star Program
- Zhongshan Science and Technology Bureau