Performance evaluation of a commercial multiplex pathogen panel for the diagnosis of pediatric joint infections
The BIOFIRE JI Panel has been limitedly evaluated in pediatric patients. Our study shows a strong agreement between the BIOFIRE JI panel and culture and/or 16S rRNA PCR with Sanger sequencing for the detection of the most common pathogenic causes of joint infection in children. The faster time to results of the BIOFIRE JI panel has the potential to guide optimal treatment faster than conventional methods.
Authors
- Mary C. Villani (ORCID: https://orcid.org/0000-0001-5370-4632)
- Naureen Tareen (ORCID: https://orcid.org/0000-0003-1826-4138)
- Laura Filkins (ORCID: https://orcid.org/0000-0002-0406-4947)
- Lawson A. Copley (ORCID: https://orcid.org/0000-0002-4325-2414)
- Gina Lee (ORCID: https://orcid.org/0000-0002-8120-9169)
Institutions
- Children's Medical Center (US)
- Baptist Health System (US)
- Cook Children's Health Care System (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of Clinical Microbiology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.1128/jcm.00278-25
- Citations
- 3
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- BioFire Diagnostics